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Andrologia. 2018 Nov 20:e13201. doi: 10.1111/and.13201. [Epub ahead of print]

Oxidative stress-mediated alterations on sperm parameters in male Wistar rats exposed to 3G mobile phone radiation.

Author information

1
School of Environmental Sciences, Jawaharlal Nehru University, New Delhi - 110067, India.

Abstract

In recent years, there has been significant increase in mobile phone users. With this, health concerns associated with the exposure to electromagnetic radiation are also increasing. Continuous exposure to electromagnetic (EM) radiation generated from mobile phone is one of the probable reasons behind increasing male infertility. EM radiations induce oxidative stress that leads to numerous changes in reproductive parameters. With this hypothesis, we studied the effect of 3G mobile phone radiations on the reproductive system of male Wistar rats. Adult rats were divided into two groups: control and radio frequency-exposed. The animals were exposed to 3G mobile phone radiation for 45 days (2 hr/day) in specially designed exposure setup under standard conditions. Various biochemical and physiological parameters such as sperm count, sperm morphology, mitochondrial activity, lipid peroxidation, reactive oxygen species level and histopathological analysis were studied. Histopathological examination revealed a reduction in spermatogenic cells and alterations in sperm membrane. Significant increase in ROS and lipid peroxidation level with simultaneously decrease in sperm count, alterations in sperm tail morphology were observed in the exposed group. In conclusion, exposure to mobile phone radiations induces oxidative stress in male Wistar rats which may lead to alteration in sperm parameters and affects their fertility.

KEYWORDS:

3G mobile phone; electromagnetic radiation; male infertility; oxidative stress; sperm parameters

PMID:
30461041
DOI:
10.1111/and.13201

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