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Clin Liver Dis. 2019 Feb;23(1):127-139. doi: 10.1016/j.cld.2018.09.007.

Liver Transplantation for Alcoholic Liver Disease: An Update.

Author information

1
Department of Student Affairs, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: Elizabeth.Godfrey@bcm.edu.
2
6620 Main Street, Suite 1425, Houston, TX 77030, USA.

Abstract

Alcoholic liver disease is a serious and increasing contributor to the global liver disease burden. Extensive selection criteria, including a minimum abstinence period, has previously been used to secure good outcomes but new research questions the effectiveness of abstinence periods and has recommended changes in integrated alcohol use treatment to effectively prevent relapse. Patients have unique health concerns, including posttransplantation risks of malignancy and metabolic complications, but overall very good long-term outcomes. Severe alcoholic hepatitis has been increasingly treated with early transplantation without a set sobriety period, with overall favorable outcomes, even with respect to recidivism.

KEYWORDS:

Alcoholic hepatitis; Alcoholic liver disease; Alcoholism; End-stage liver disease; Liver transplantation

PMID:
30454827
DOI:
10.1016/j.cld.2018.09.007

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