Format

Send to

Choose Destination
Sci Rep. 2018 Nov 19;8(1):17008. doi: 10.1038/s41598-018-35215-8.

Atypical postural control can be detected via computer vision analysis in toddlers with autism spectrum disorder.

Author information

1
Duke Center for Autism and Brain Development, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA. geraldine.dawson@duke.edu.
2
University of Utah, Salt Lake City, Utah, USA.
3
Duke Center for Autism and Brain Development, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA.
4
Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina, USA.
5
Department of Population Health Sciences, Duke University, Durham, North Carolina, USA.
6
NYU Langone Child Study Center, New York University, New York, New York, USA.
7
Department of Pediatrics, Duke University, Durham, NC, USA.
8
Departments of Biomedical Engineering, Computer Science, and Mathematics, Duke University, Durham, NC, USA.

Abstract

Evidence suggests that differences in motor function are an early feature of autism spectrum disorder (ASD). One aspect of motor ability that develops during childhood is postural control, reflected in the ability to maintain a steady head and body position without excessive sway. Observational studies have documented differences in postural control in older children with ASD. The present study used computer vision analysis to assess midline head postural control, as reflected in the rate of spontaneous head movements during states of active attention, in 104 toddlers between 16-31 months of age (Mean = 22 months), 22 of whom were diagnosed with ASD. Time-series data revealed robust group differences in the rate of head movements while the toddlers watched movies depicting social and nonsocial stimuli. Toddlers with ASD exhibited a significantly higher rate of head movement as compared to non-ASD toddlers, suggesting difficulties in maintaining midline position of the head while engaging attentional systems. The use of digital phenotyping approaches, such as computer vision analysis, to quantify variation in early motor behaviors will allow for more precise, objective, and quantitative characterization of early motor signatures and potentially provide new automated methods for early autism risk identification.

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center