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J Int Med Res. 1988 May-Jun;16(3):244-8.

Comparison of flavoxate hydrochloride in daily dosages of 600 versus 1200 mg for the treatment of urgency and urge incontinence.

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1
Department of Obstetrics and Gynaecology, University of Milan, San Gerardo Hospital, Monza, Italy.

Abstract

Flavoxate hydrochloride at a daily dosage of 600 mg was compared to a daily dosage of 1200 mg for the treatment of unstable bladder. Twenty-seven patients were treated for 4 weeks in a double-blind, randomized, parallel-group trial. Clinically, both schedules were equally successful. In urodynamic terms, however, particularly with respect to uninhibited detrusor contractions, 1200 mg/day was significantly superior to 600 mg/day. Tolerability was excellent for both regimens. The side-effect free treatment of urgency and urge incontinence is of paramount importance for a patient's quality of life.

PMID:
3044876
DOI:
10.1177/030006058801600313
[Indexed for MEDLINE]
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