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Crit Care Nurs Clin North Am. 2018 Dec;30(4):563-583. doi: 10.1016/j.cnc.2018.07.010.

Neuroprotective Care of Extremely Preterm Infants in the First 72 Hours After Birth.

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Northeastern University, School of Nursing in the Bouvé College of Health Sciences, 360 Huntington Avenue, Boston, MA 02115, USA; Philips HealthTech, Cambridge, MA, USA. Electronic address:
Loma Linda University School of Medicine, Department of Pediatrics, Division of Neonatology, Loma Linda University Children's Hospital, 11175 Campus Street, CP 11121 Loma Linda, CA 92354, USA; Loma Linda University Medical Center-Murrieta, 28062 Baxtor Road, Murrieta, CA 92563, USA.


Birth at extremely low gestational ages presents a significant threat to infants' survival, health, development, and future well-being. After birth, a critical period of brain development must continue outside the womb. Neuro-supportive and neuroprotective family centered developmental care for and standardized care practices for extremely preterm infants have been shown to improve outcomes. Neuroprotective interventions must include a focus on the emotional connections of infants and their families. Being in skin-to-skin contact with the mother is the developmentally expected environment for all mammals and is especially important for supporting physiologic stability and neurodevelopment of preterm infants.


Core measures; Developmental care; Integrative; Neonatal; Neuroprotection; Small baby programs

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