Format

Send to

Choose Destination
See comment in PubMed Commons below
Mol Cell Biol. 1988 Jun;8(6):2651-4.

B-raf, a new member of the raf family, is activated by DNA rearrangement.

Author information

1
Department of Oncology, University of Tokyo, Japan.

Abstract

Complementary DNA clones of a putative transforming gene were isolated from NIH 3T3 cells transformed with human Ewing sarcoma DNA. The gene was termed B-raf because it is related to but distinct from c-raf and A-raf. It appears that substitution in the amino-terminal portion of the normal B-raf protein confers transforming activity to the gene.

PMID:
3043188
PMCID:
PMC363468
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center