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South Asian J Cancer. 2018 Oct-Dec;7(4):240-243. doi: 10.4103/sajc.sajc_241_17.

Age-adjusted charlson comorbidity index and 30-day morbidity in pelvic surgeries.

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Department of Surgical Oncology, Malabar Cancer Center, Kannur, Kerala, India.



Charlson comorbidity index (CCI) is a validated tool enabling clinicians for prediction of adverse events posttherapy. In this study, we planned to estimate the predictive value of age-adjusted CCI (ACCI) in assessing the perioperative complication in oncological patients undergoing major pelvic surgeries.


This was a single arm, prospective, observational study, in which adult patients with pelvic malignancies undergoing pelvic surgeries were selected. The relationship between the ACCI and Grade 3-5 adverse events were tested using Fisher's test.


The rate of Grade 3-5 adverse event rate was 16.7% (11 patients, n = 66). Among the whole cohort, 11 patients (16.7%) had high score on ACCI. The rate of Grade 3-5 adverse events was higher in the cohort of patients with high ACCI score (45.5% vs. 10.9%, P = 0.014). The sensitivity, specificity and negative and positive predictive values were 45.5%, 89.1%, 89.1%, and 45.5%, respectively.


ACCI can predict for postsurgical adverse events. It has a high negative predictive value for nonoccurrence of adverse events.


Adverse events; Charlson comorbidity index; age adjusted Charlson comorbidity index; complications; pelvic; surgeries

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