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Mater Sci Eng C Mater Biol Appl. 2019 Jan 1;94:445-452. doi: 10.1016/j.msec.2018.09.058. Epub 2018 Sep 22.

Preparation and characterization of Aloe vera acetate and electrospinning fibers as promising antibacterial properties materials.

Author information

1
School of Chemistry, Alborz Campus, University of Tehran, Tehran, Iran.
2
School of Chemistry, Alborz Campus, University of Tehran, Tehran, Iran. Electronic address: nsanjani@khayam.ut.ac.ir.
3
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Iran.
4
Center for Research & Training in Skin Diseases and Leprosy (CRTSDL), Tehran University Medical of Science, P.O. Box 1416613675, Tehran, Iran.

Abstract

In this work, the anti-bacterial effect of Aloe vera derivate fibers produced by the electrospinning method was reported. Aloe vera Polyvinylpyrrolidone (Av/PVP) and Aloe vera acetate-Polyvinylpyrrolidone (AvAc/PVP) electrospun fibers were prepared with different concentrations and their microstructure and mechanical properties were studied. Various methods such as differential scanning calorimetry (DSC), thermogravimetry analysis (TGA), water contact angle (CA) tests, Fourier-Transform Nuclear Magnetic Resonance (FT-NMR), scanning electron microscope (SEM), X-ray diffraction (XRD), CHNSO and Fourier-Transform Infrared Spectroscopy (FT-IR) were used to characterize prepared samples. (Av/PVP) electrospun fibers were prepared with different concentrations (6-10 wt%) of PVP and 0.2 wt% Av blended and tested in medicinal herb for wound healing, antibacterial and anti-inflammatory properties. For further study, the effect of AvAc film on the properties of composite film was studied. AvAc increased the thermal stability and crystallite size percentage of samples. Antibacterial and antiviral test studies on the scaffold displayed no bacterial and viral growth. These results suggest that AvAc/PVP scaffolds could be promising candidates for wound healing applications.

KEYWORDS:

Acetylation; Aloe barbadensis Miller; Electrospinning; Nano fibers; Structural modifications; Wound healing

PMID:
30423728
DOI:
10.1016/j.msec.2018.09.058
[Indexed for MEDLINE]

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