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Caffeine Toxicity.


Murray A1, Traylor J2.


StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020-.
2019 Nov 11.

Author information

Mercy St. Vincent Medical Center
Grandview Hospital


Caffeine is a stimulant that has been utilized globally for centuries secondary to its ability to improve mental alertness. As many as 85% of Americans consume caffeine daily with the average cup of coffee containing anywhere from 40 to 150 mg of caffeine.[1] Caffeine can be found in many over-the-counter preparations (energy drinks, appetite suppressants, stimulants, exercise supplements, decongestants, bronchodilators, and mental stimulants), increasing the risk of toxicity with inadvertent overuse or severe toxicity with an intentional overdose.[2] Lethal doses of caffeine have been reported at blood concentrations of 80 to 100 micrograms/ml which can be reached with ingestion of approximately 10 grams or greater.[3][4][5][6][7]

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