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Clin Imaging. 2019 Jan - Feb;53:195-199. doi: 10.1016/j.clinimag.2018.10.024. Epub 2018 Oct 31.

Relationship between current smoking, visual CT findings and emphysema index in cigarette smokers.

Author information

1
Department of Radiology, Soonchunhyang University Cheonan Hospital, 31 Soonchunhyang 6-gil, Dongnamgu, Cheonan-si, Chungchengnam-do 311511, Republic of Korea. Electronic address: ssmri@schmc.ac.kr.
2
Department of Radiology, St. Marianna University School of Medicine, 2-16-1, Sugao, Miyamae-ku, Kawasaki 216-8511, Japan.
3
Division of Radiology, National Jewish Health, Denver, CO, United States of America.
4
Department of Biomedical Sciences College of Medicine, Inha University Incheon, Republic of Korea.

Abstract

PURPOSE:

To evaluate whether visual CT findings could account for the effect of current smoking.

METHODS:

500 CT scans were visually evaluated within each lobe. A multivariate model for emphysema index was constructed containing previously described confounders in addition to the visual components associated with smoking status.

RESULTS:

Current smokers displayed 23% less visual emphysema, 19% more airway wall thickening, and 188% more centrilogular nodule than former smokers (all p < 0.001). The effect of current smoking on the emphysema index decreased after adjustment with confounders and visual parameters.

CONCLUSIONS:

Visual CT findings could partially account for the effect of current smoking.

KEYWORDS:

Chronic obstructive pulmonary disease; Emphysema; Quantitative computed tomography; Smoking

PMID:
30419414
DOI:
10.1016/j.clinimag.2018.10.024
[Indexed for MEDLINE]

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