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J Perioper Pract. 2018 Nov 12:1750458918812293. doi: 10.1177/1750458918812293. [Epub ahead of print]

Postoperative stress and pain response applying fast-track protocol in patients undergoing hepatectomy.

Author information

1
1 Chief Nurse of PACU, Hellenic Anticancer Hospital "Saint Savvas", Day Care Surgery "N. KOURKOULOS" Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece.
2
2 Department of Nursing, National and Kapodistrian University of Athens, Athens, Greece.
3
3 Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece.

Abstract

AIM:

To assess the clinical parameters and compare the stress and pain response between fast-track recovery protocol and conventional treatment in patients undergoing major liver resection.

METHODS:

Eighty-eight patients suffering from malignant liver tumours were surgically treated from May 2012 to March 2015. After randomisation, they were prospectively divided into two groups: group fast-track patients (nā€‰=ā€‰46) and group conventional treatment patients (nā€‰=ā€‰42). Demographic and clinical data were collected and patients were assessed with pain scale (behavioural observation scale and visual analog scale), while depression levels were evaluated with Zung self-rating depression scale and three Numeric Analog Scale self-reported questions. Peripheral blood samples were collected at time points: T1 on the admission day, T2 on the day of surgery and T3 on the day of discharge examining serum levels of adrenocorticotropic hormone and cortisol.

CONCLUSION:

Fast-track recovery protocols seem to be associated with improvement in several clinical parameters, without compromising, biologic or emotional stress in patients undergoing major liver resection.

KEYWORDS:

Enhanced recovery program after liver resection; Fast-track after liver resection; Pain response; Stress response; Surgery trauma

PMID:
30417764
DOI:
10.1177/1750458918812293

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