Format

Send to

Choose Destination
J Bone Jt Infect. 2018 Oct 4;3(4):207-211. doi: 10.7150/jbji.27811. eCollection 2018.

Daptomycin Plus Fosfomycin as Salvage Therapy in a Difficult-to-Treat Total Femoral Replacement Infection.

Author information

1
Department of Orthopaedic surgery and Traumatology, Hospital Universitario 12 de Octubre. Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12). Madrid, Spain.
2
Department of Internal Medicine, Hospital Universitario 12 de Octubre. Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12). Madrid, Spain.
3
Department of Microbiology, Hospital Universitario 12 de Octubre. Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12). Madrid, Spain.
4
Department of Plastic Surgery, Hospital Universitario 12 de Octubre. Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12). Madrid, Spain.

Abstract

The highly active anti-biofilm combination of daptomycin plus fosfomycin was successfully used in a difficult-to-treat infection of a total femoral replacement caused by multi-drug resistant Staphylococcus epidermidis in a 79-year-old woman. There was no need to remove the orthopedic hardware, and the patient is currently pain free and able to walk.

KEYWORDS:

Staphylococcus; biofilm; bone and joint infection; prosthetic joint infection

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

Supplemental Content

Full text links

Icon for Ivyspring International Publisher Icon for PubMed Central
Loading ...
Support Center