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Rheum Dis Clin North Am. 1988 Apr;14(1):99-116.

Musculoskeletal manifestations of systemic lupus erythematosus.

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Loyola University Stritch School of Medicine, Rheumatology Section, Maywood, Illinois.


The musculoskeletal system is involved in nearly all patients with SLE. Transient arthralgias or arthritis are common and, in some patients, there is a progression to rheumatoid-like nonerosive hand deformities (Jaccoud's syndrome). The major disabling type of joint disease in lupus is articular osteonecrosis, often induced by high-dose corticosteroids. Rare forms of musculoskeletal manifestations of lupus include spontaneous tendon rupture, crystalline arthropathies, subcutaneous calcifications, and inflammatory myopathy.

[Indexed for MEDLINE]

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