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Curr Nutr Rep. 2018 Dec;7(4):335-345. doi: 10.1007/s13668-018-0247-9.

Dietary Patterns, Physical Activity, Sleep, and Risk for Dementia and Cognitive Decline.

Zhao C1,2, Noble JM3,4,5, Marder K3,4,5, Hartman JS6, Gu Y4,5,7, Scarmeas N3,4,5,8.

Author information

1
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA. cz2457@cumc.columbia.edu.
2
Taub Institute for Research of Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA. cz2457@cumc.columbia.edu.
3
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
4
Taub Institute for Research of Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA.
5
Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.
6
Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA.
7
Department of Epidemiology, Joseph P. Mailman School of Public Health, Columbia University, New York, NY, USA.
8
1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.

Abstract

PURPOSE OF REVIEW:

Diet, physical activity, and sleep are three major modifiable lifestyle factors. This selective review examines the evidence for strong and reliable associations between these three lifestyle factors and risk of dementia and cognitive decline, in an effort to assist clinicians with providing more informed answers to the common questions they face from patients.

RECENT FINDINGS:

Certain aspects of nutrition can decrease risk for dementia. Physical activity has also been associated with delayed or slower age-related cognitive decline. In addition, emerging evidence links sleep dysfunction and dementia, with amyloid deposition being a possible mediator. Data from further clinical trials are needed before more definitive conclusions can be drawn regarding the efficacy of these lifestyle interventions for lowering the risk of incident dementia and cognitive decline. Nevertheless, it is reasonable to make recommendations to our patients to adopt certain dietary changes and to engage in regular physical activity to improve cardiovascular risk factors for dementia. It is also reasonable to include questions on sleep during cognitive evaluations of the elderly, given the common co-occurrence of sleep dysfunction and cognitive impairment in the elderly population.

KEYWORDS:

Diet and cognition; Diet and dementia; Exercise and cognition; Exercise and dementia; Lifestyle and cognition; Lifestyle and dementia; Modifiable factors dementia; Nutrition and cognition; Nutrition and dementia; Physical activity and cognition; Physical activity and dementia; Prevent dementia; Primary prevention dementia; Risk factors dementia; Sleep and cognition; Sleep and dementia

PMID:
30413973
DOI:
10.1007/s13668-018-0247-9
[Indexed for MEDLINE]

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