Antimutagenic effect of volatile decomposition products from thermally oxidized linoleate

Mutat Res. 1988 Jul;208(3-4):163-6. doi: 10.1016/0165-7992(88)90054-1.

Abstract

The antimutagenic effect of volatile decomposition products from thermally oxidized linoleate on mutagenesis by UV irradiation was investigated in Escherichia coli B/r WP2. When added to an agar medium, these products greatly reduced the number of Trp+ revertants. The same antimutagenic effect was observed by acrolein, 2-hexenal, 2-heptenal, 2-nonenal and 2,4-decadienal; these unsaturated aldehydes were components of volatile products.

MeSH terms

  • Acrolein
  • Aldehydes / pharmacology*
  • Escherichia coli / drug effects
  • Escherichia coli / genetics
  • Hot Temperature
  • Linoleic Acids*
  • Mutagenicity Tests
  • Mutagens / antagonists & inhibitors*
  • Mutation / radiation effects
  • Oxidation-Reduction
  • Ultraviolet Rays

Substances

  • Aldehydes
  • Linoleic Acids
  • Mutagens
  • Acrolein