Format

Send to

Choose Destination
Neuron. 2018 Nov 7;100(3):511-513. doi: 10.1016/j.neuron.2018.10.039.

Inflamed Astrocytes: A Path to Depression Led by Menin.

Author information

1
Department of Psychiatry and Neuroscience, Faculty of Medicine & CERVO Brain Research Center, Université Laval, Quebec City, QC G1J 2G3, Canada; Department of Biochemistry, Federal University of Santa Catarina, Florianopolis, Brazil.
2
Department of Psychiatry and Neuroscience, Faculty of Medicine & CERVO Brain Research Center, Université Laval, Quebec City, QC G1J 2G3, Canada. Electronic address: caroline.menard@fmed.ulaval.ca.

Abstract

Increasing evidence supports a role for inflammation in the development of mood disorders. In this issue of Neuron, Leng et al. (2018) show that reduction of menin expression in astrocytes of stress-related brain regions exacerbates neuroinflammation, promoting the establishment of depression-like behaviors in mice.

PMID:
30408435
DOI:
10.1016/j.neuron.2018.10.039
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center