Novel key cytokines in allergy: IL-17, IL-22

S Eyerich; C Traidl-Hoffmann; H Behrendt; A Cavani; C B Schmidt-Weber; J Ring; K Eyerich

doi:10.5414/ALX01403E

Novel key cytokines in allergy: IL-17, IL-22

Allergol Select. 2017 Aug 4;1(1):71-76. doi: 10.5414/ALX01403E. eCollection 2017.

Authors

S Eyerich¹, C Traidl-Hoffmann^{1

2}, H Behrendt¹, A Cavani³, C B Schmidt-Weber¹, J Ring², K Eyerich²

Affiliations

¹ ZAUM - Zentrum Allergie & Umwelt, Technische Universität und Helmholtz-Zentrum München, Munich, Germany.
² Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München, Munich, Germany.
³ Laboratory of Immunology, Istituto Dermopatico DellImmacolata, Rome, Italy.

Abstract

The biology of the T cell cytokines Interleukin (IL-)17 and IL-22 has been a main focus in the field of clinical immunology in the last decade. This intensive interest in both cytokines has resulted in almost 5,000 scientific publications (www.pubmed.com) dealing with the molecular structure, extra- and intracellular signaling pathways, specific transcription factors and the function of IL-17 and IL-22. This review article highlights the main findings concerning IL-17 and IL-22 in the last years.

Keywords: IL-17; IL-22; T cell; cytokine; immunology.

Publication types

Review