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Open Forum Infect Dis. 2018 Nov 1;5(11):ofy244. doi: 10.1093/ofid/ofy244. eCollection 2018 Nov.

Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient.

Author information

1
Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
2
Institute of Pathology, University of Bern, Bern, Switzerland.
3
Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
4
Department of Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Abstract

We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage is crucial in protecting vulnerable subjects.

KEYWORDS:

immunocompromised; measles; rituximab; vaccination

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