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Clin Transl Allergy. 2018 Oct 25;8:45. doi: 10.1186/s13601-018-0227-6. eCollection 2018.

MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence.

Collaborators (429)

Bousquet J, Hellings PW, Aberer W, Agache I, Akdis CA, Akdis M, Alberti MR, Almeida R, Amat F, Angles R, Annesi-Maesano I, Ansotegui IJ, Anto JM, Arnavielle S, Asayag E, Asarnoj A, Arshad H, Avolio F, Bacci E, Bachert C, Baiardini I, Barbara C, Barbagallo M, Baroni I, Barreto BA, Basagana X, Bateman ED, Bedolla-Barajas M, Bedbrook A, Bewick M, Beghé B, Bel EH, Bergmann KC, Bennoor KS, Benson M, Bertorello L, Bialoszewski AZ, Bieber T, Bialek S, Bindslev-Jensen C, Bjermer L, Blain H, Blasi F, Blua A, Bochenska Marciniak M, Bogus-Buczynska I, Boner AL, Bonini M, Bonini S, Bosnic-Anticevich CS, Bosse I, Bouchard J, Boulet LP, Bourret R, Bousquet PJ, Braido F, Briedis V, Brightling CE, Brozek J, Bucca C, Buhl R, Buonaiuto R, Panaitescu C, Burguete Cabañas MT, Burte E, Bush A, Caballero-Fonseca F, Caillot D, Caimmi D, Calderon MA, Camargos PAM, Camuzat T, Canfora G, Canonica GW, Cardona V, Carlsen KH, Carreiro-Martins P, Carriazo AM, Carr W, Cartier C, Casale T, Castellano G, Cecchi L, Cepeda Sarabia AM, Chavannes NH, Chen Y, Chiron R, Chivato T, Chkhartishvili E, Chuchalin AG, Chung KF, Ciaravolo MM, Ciceran A, Cingi C, Ciprandi G, Carvalho Coehlo AC, Colas L, Colgan E, Coll J, Conforti D, de Sousa JC, Cortés-Grimaldo RM, Corti F, Costa E, Costa-Dominguez MC, Courbis AL, Cox L, Crescenzo M, Cruz AA, Custovic A, Czarlewski W, Dahlen SE, Dario C, da Silva J, Dauvilliers Y, Darsow U, De Blay F, De Carlo G, Dedeu T, de Fátima Emerson M, De Feo G, De Vries G, De Martino B, de Paula Motta Rubini N, Deleanu D, Demoly P, Denburg JA, Devillier P, Di Capua Ercolano S, Di Carluccio N, Didier A, Dokic D, Dominguez-Silva MG, Douagui H, Dray G, Dubakiene R, Durham SR, Du Toit G, Dykewicz MS, El-Gamal Y, Eklund P, Eller E, Emuzyte R, Farrell J, Farsi A, de Mello JF Jr, Ferrero J, Fink-Wagner A, Fiocchi A, Fokkens WJ, Fonseca JA, Fontaine JF, Forti S, Fuentes-Perez JM, Gálvez-Romero JL, Gamkrelidze A, Garcia-Aymerich J, García-Cobas CY, Garcia-Cruz MH, Gemicioglu B, Genova S, George C, Gereda JE, van Wijk RG, Gomez RM, Gómez-Vera J, González Diaz S, Gotua M, Grisle I, Guidacci M, Guldemond NA, Gutter Z, Guzmán MA, Haahtela T, Hajjam J, Hernández L, O'B Hourihane J, Huerta-Villalobos YR, Humbert M, Iaccarino G, Illario M, Ivancevich JC, Jares EJ, Jassem E, Johnston SL, Joos G, Jung KS, Jutel M, Kaidashev I, Kalayci O, Kalyoncu AF, Karjalainen J, Kardas P, Keil T, Keith PK, Khaitov M, Khaltaev N, Kleine-Tebbe J, Klimek L, Kowalski ML, Kuitunen M, Kull I, Kuna P, Kupczyk M, Kvedariene V, Krzych-Falta E, Lacwik P, Larenas-Linnemann D, Laune D, Lauri D, Lavrut J, Le LTT, Lessa M, Levato G, Li J, Lieberman P, Lipiec A, Lipworth B, Lodrup Carlsen KC, Louis R, Lourenço O, Luna-Pech JA, Maciej K, Magnan A, Mahboub B, Maier D, Mair A, Majer I, Malva J, Mandajieva E, Manning P, De Manuel Keenoy E, Marshall GD, Masjedi MR, Maspero JF, Mathieu-Dupas E, Matta Campos JJ, Matos AL, Maurer M, Mavale-Manuel S, Mayora O, Medina-Avalos MA, Melén E, Melo-Gomes E, Meltzer EO, Menditto E, Mercier J, Miculinic N, Mihaltan F, Milenkovic B, Moda G, Mogica-Martinez MD, Mohammad Y, Momas I, Montefort S, Monti R, Mora Bogado D, Morais-Almeida M, Morato-Castro FF, Mösges R, Mota-Pinto A, Moura Santo P, Mullol J, Münter L, Muraro A, Murray R, Naclerio R, Nadif R, Nalin M, Napoli L, Namazova-Baranova L, Neffen H, Niedeberger V, Nekam K, Neou A, Nieto A, Nogueira-Silva L, Nogues M, Novellino E, Nyembue TD, O'Hehir RE, Odzhakova C, Ohta K, Okamoto Y, Okubo K, Onorato GL, Ortega Cisneros M, Ouedraogo S, Pali-Schöll I, Palkonen S, Panzner P, Papadopoulos NG, Park HS, Papi A, Passalacqua G, Paulino E, Pawankar R, Pedersen S, Pépin JL, Pereira AM, Persico M, Pfaar O, Phillips J, Picard R, Pigearias B, Pin I, Pitsios C, Plavec D, Pohl W, Popov TA, Portejoie F, Potter P, Pozzi AC, Price D, Prokopakis EP, Puy R, Pugin B, Pulido Ross RE, Przemecka M, Rabe KF, Raciborski F, Rajabian-Soderlund R, Reitsma S, Ribeirinho I, Rimmer J, Rivero-Yeverino D, Rizzo JA, Rizzo MC, Robalo-Cordeiro C, Rodenas F, Rodo X, Rodriguez Gonzalez M, Rodriguez-Mañas L, Rolland C, Rodrigues Valle S, Roman Rodriguez M, Romano A, Rodriguez-Zagal E, Rolla G, Roller-Wirnsberger RE, Romano M, Rosado-Pinto J, Rosario N, Rottem M, Ryan D, Sagara H, Salimäki J, Samolinski B, Sanchez-Borges M, Sastre-Dominguez J, Scadding GK, Schunemann HJ, Scichilone N, Schmid-Grendelmeier P, Serpa FS, Shamai S, Sheikh A, Sierra M, Simons FER, Siroux V, Sisul JC, Skrindo I, Solé D, Somekh D, Sondermann M, Sooronbaev T, Sova M, Sorensen M, Sorlini M, Spranger O, Stellato C, Stelmach R, Stukas R, Sunyer J, Strozek J, Szylling A, Tebyriçá JN, Thibaudon M, To T, Todo-Bom A, Tomazic PV, Toppila-Salmi S, Trama U, Triggiani M, Suppli Ulrik C, Urrutia-Pereira M, Valenta R, Valero A, Valiulis A, Valovirta E, van Eerd M, van Ganse E, van Hague M, Vandenplas O, Ventura MT, Vezzani G, Vasankari T, Vatrella A, Verissimo MT, Viart F, Viegi M, Vicheva D, Vontetsianos T, Wagenmann M, Walker S, Wallace D, Wang DY, Waserman S, Werfel T, Westman M, Wickman M, Williams DM, Williams S, Wilson N, Wright J, Wroczynski P, Yakovliev P, Yawn BP, Yiallouros PK, Yorgancioglu A, Yusuf OM, Zar HJ, Zhang L, Zhong N, Zernotti ME, Zidarn M, Zuberbier T, Zubrinich C, Zurkuhlen A.

Abstract

mHealth, such as apps running on consumer smart devices is becoming increasingly popular and has the potential to profoundly affect healthcare and health outcomes. However, it may be disruptive and results achieved are not always reaching the goals. Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline using the best evidence-based approach to care pathways suited to real-life using mobile technology in allergic rhinitis (AR) and asthma multimorbidity. Patients largely use over-the-counter medications dispensed in pharmacies. Shared decision making centered around the patient and based on self-management should be the norm. Mobile Airways Sentinel networK (MASK), the Phase 3 ARIA initiative, is based on the freely available MASK app (the Allergy Diary, Android and iOS platforms). MASK is available in 16 languages and deployed in 23 countries. The present paper provides an overview of the methods used in MASK and the key results obtained to date. These include a novel phenotypic characterization of the patients, confirmation of the impact of allergic rhinitis on work productivity and treatment patterns in real life. Most patients appear to self-medicate, are often non-adherent and do not follow guidelines. Moreover, the Allergy Diary is able to distinguish between AR medications. The potential usefulness of MASK will be further explored by POLLAR (Impact of Air Pollution on Asthma and Rhinitis), a new Horizon 2020 project using the Allergy Diary.

KEYWORDS:

ARIA; App; Asthma; Care pathways; MASK; Rhinitis; mHealth

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