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Urol Ann. 2018 Oct-Dec;10(4):413-415. doi: 10.4103/UA.UA_182_17.

Primitive neuroectodermal tumor transformation of testicular teratoma.

Author information

1
Department of Urology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
2
Department of Medical Oncology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
3
Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Abstract

Malignant transformation of teratoma develops in a small subset of testis cancer patients. Primitive neuroectodermal tumor represents a highly malignant component of testicular germ cell tumors. It is a rare clinical entity which is characterized by a high risk of disease progression and death. Surgical resection plus chemotherapy appears to be the therapy of choice.

KEYWORDS:

Germ cell tumor; malignant transformation of teratoma; primitive neuroectodermal tumor; retroperitoneal lymph node dissection

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