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Infect Dis Poverty. 2018 Nov 2;7(1):104. doi: 10.1186/s40249-018-0486-4.

Geographic distribution of echinococcosis in Tibetan region of Sichuan Province, China.

Author information

1
Department of Parasitic Diseases, Sichuan Center for Disease Control and Prevention, No.6 Zhongxue Road, Chengdu, 610041, China.
2
West China School of Public Health, Sichuan University, No.16 3rd Section of Renmin South Road, Chengdu, 610041, China.
3
Ganzi Center for Disease Control and Prevention, No.139 Lucheng South Road, Ganzi Prefecture, 626000, China.
4
Department of Parasitic Diseases, Sichuan Center for Disease Control and Prevention, No.6 Zhongxue Road, Chengdu, 610041, China. zhongbo1968@163.com.
5
Aba Center for Disease Control and Prevention, No.178 Meigu Street, Aba Prefecture, 624000, China.

Abstract

BACKGROUND:

Echinococcosis is a parasitic zoonosis caused by Echinococcus larvae parasitism causing high mortality. The Tibetan Region of Sichuan Province is a high prevalence area for echinococcosis in China. Understanding the geographic distribution pattern is necessary for precise control and prevention. In this study, a spatial analysis was conducted to explore the town-level epidemiology of echinococcosis in the Sichuan Tibetan Region and to provide guidance for formulating regional prevention and control strategies.

METHODS:

The study was based on reported echinococcosis cases by the end of 2017, and each case was geo-coded at the town level. Spatial empirical Bayes smoothing and global spatial autocorrelation were used to detect the spatial distribution pattern. Spatial scan statistics were applied to examine local clusters.

RESULTS:

The spatial distribution of echinococcosis in the Sichuan Tibetan Region was mapped at the town level in terms of the crude prevalence rate, excess hazard and spatial smoothed prevalence rate. The spatial distribution of echinococcosis was non-random and clustered with the significant global spatial autocorrelation (I = 0.7301, P = 0.001). Additionally, five significant spatial clusters were detected through the spatial scan statistic.

CONCLUSIONS:

There was evidence for the existence of significant echinococcosis clusters in the Tibetan Region of Sichuan Province, China. The results of this study may assist local health departments with developing better prevention strategies and prompt more efficient public health interventions.

KEYWORDS:

Echinococcosis; Moran’s I; Spatial autocorrelation analysis; Spatial cluster analysis

PMID:
30384860
PMCID:
PMC6214160
DOI:
10.1186/s40249-018-0486-4
[Indexed for MEDLINE]
Free PMC Article

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