1 Institute for Biochemistry II and Frankfurt Cancer Institute, Goethe University, Theodor Stern Kai 7, 60590, Frankfurt, Germany. dikic@biochem2.uni-frankfurt.de.
The endoplasmic reticulum (ER) is one of the most complex organelles in the eukaryotic cell. Recent findings suggest that a process called ER-phagy plays a major role in maintaining the ER's shape and function.