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Ann N Y Acad Sci. 1987;496:166-9.

Possible correction of defective polymorphonuclear cell functions in type-2 diabetes mellitus by met-enkephalin.


In vitro pretreatment with Met-Enk of human PMNLs obtained from patients suffering from type-2 diabetes mellitus resulted in the normalization of the ROS generating system. It is assumed that Met-Enk has a modulating effect on the arachidonic acid metabolism, with a consecutive increase of the LTB4 release.

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