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Asian Pac J Cancer Prev. 2018 Oct 26;19(10):2979-2984.

The Effect of Gluten Free Diet on Components of Metabolic Syndrome: A Randomized Clinical Trial

Author information

1
Department of Clinical Nutrition and Dietetics,, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Email: a_hekmat2000@yahoo.com

Abstract

BACKGROUND:

This study aimed to assess the effects of Gluten free diet (GFD) on components of metabolic syndrome (MES).

MATERIALS AND METHODS:

In this randomized clinical trial, 50 subjects diagnosed with MES were randomly divided into two groups (n=25). The first group received a GFD and the second group continued their regular diet. Biochemical markers of MES and blood pressure were measured before and after 8-week intervention.

RESULTS:

Forty five subjects completed the study. A post-hoc comparison of the groups showed no effects of the GFD and control diet on LDL cholesterol, total cholesterol, fasting insulin, HOMA-IR, systolic and diastolic blood pressure levels. The GFD reduced fasting blood glucose, waist circumference (WC) and serum triglyceride concentration significantly compared with the control diet (p<0.05).

CONCLUSION:

Short-term GFD reduced WC and improved glycemic control and Triglyceride level in subjects with the metabolic syndrome.

KEYWORDS:

Gluten free diet; metabolic syndrome; obesity

PMID:
30362336
PMCID:
PMC6291063
DOI:
10.22034/APJCP.2018.19.10.2979
[Indexed for MEDLINE]
Free PMC Article

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