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Arch Virol. 1987;94(3-4):323-9.

Effect of recombinant human interferon gamma against human cytomegalovirus.

Abstract

Escherichia coli-derived human interferon-gamma (rIFN-gamma) inhibited the replication of human cytomegalovirus (HCMV) synergistically when combined with IFN-alpha. The induction of HCMV DNA polymerase was inhibited in rIFN-gamma-treated cells. It is suggested that the induction of 2-5 A synthetase does not play an important role in the anti-HCMV actions of IFNs.

PMID:
3034215
DOI:
10.1007/bf01310726
[Indexed for MEDLINE]

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