Format

Send to

Choose Destination
Br J Sports Med. 2018 Nov;52(21):1357-1366. doi: 10.1136/bjsports-2018-099829.

Glucose responses to acute and chronic exercise during pregnancy: a systematic review and meta-analysis.

Author information

1
Program for Pregnancy and Postpartum Health, Physical Activity and Diabetes Laboratory, Faculty of Kinesiology, Sport and Recreation, Women and Children's Health Research Institute, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.
2
R Samuel McLaughlin Foundation - Exercise and Pregnancy Laboratory, School of Kinesiology, Faculty of Health Sciences, Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, Children's Health Research Institute, The University of Western Ontario, London, Ontario, Canada.
3
Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
4
Independent Researcher, Ottawa, Ontario, Canada.
5
Healthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
6
Clinical Research Unit, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
7
Department of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Quebec, Canada.
8
John W Scott Health Sciences Library, University of Alberta, Edmonton, Alberta, Canada.
9
Faculty of Health Science, University of Ottawa, Ottawa, Ontario, Canada.
10
Department of Obstetrics and Gynecology, Queen's University, Kingston, Ontario, Canada.
11
Facultad de Ciencias de la Actividad Física y del Deporte-INEF, Universidad Politécnica de Madrid, Madrid, Spain.
12
Department of Human Kinetics, Université du Québec à Trois-Rivières, Trois-Rivières, Quebec, Canada.

Abstract

OBJECTIVE:

To perform a systematic review and meta-analysis to explore the relationship between prenatal exercise and glycaemic control.

DESIGN:

Systematic review with random-effects meta-analysis and meta-regression.

DATA SOURCES:

Online databases were searched up to 6 January 2017.

STUDY ELIGIBILITY CRITERIA:

Studies of all designs were included (except case studies and reviews) if they were published in English, Spanish or French, and contained information on the population (pregnant women without contraindication to exercise), intervention (subjective or objective measures of frequency, intensity, duration, volume or type of acute or chronic exercise, alone ('exercise-only') or in combination with other intervention components (eg, dietary; 'exercise+cointervention') at any stage of pregnancy), comparator (no exercise or different frequency, intensity, duration, volume and type of exercise) and outcome (glycaemic control).

RESULTS:

A total of 58 studies (n=8699) were included. There was 'very low' quality evidence showing that an acute bout of exercise was associated with a decrease in maternal blood glucose from before to during exercise (6 studies, n=123; mean difference (MD) -0.94 mmol/L, 95% CI -1.18 to -0.70, I2=41%) and following exercise (n=333; MD -0.57 mmol/L, 95% CI -0.72 to -0.41, I2=72%). Subgroup analysis showed that there were larger decreases in blood glucose following acute exercise in women with diabetes (n=26; MD -1.42, 95% CI -1.69 to -1.16, I2=8%) compared with those without diabetes (n=285; MD -0.46, 95% CI -0.60 to -0.32, I2=62%). Finally, chronic exercise-only interventions reduced fasting blood glucose compared with no exercise postintervention in women with diabetes (2 studies, n=70; MD -2.76, 95% CI -3.18 to -2.34, I2=52%; 'low' quality of evidence), but not in those without diabetes (9 studies, n=2174; MD -0.05, 95% CI -0.16 to 0.05, I2=79%).

CONCLUSION:

Acute and chronic prenatal exercise reduced maternal circulating blood glucose concentrations, with a larger effect in women with diabetes.

KEYWORDS:

exercise; glucose; pregnancy

PMID:
30337462
DOI:
10.1136/bjsports-2018-099829
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center