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Clin Oral Investig. 2019 Jun;23(6):2667-2673. doi: 10.1007/s00784-018-2675-8. Epub 2018 Oct 17.

In vivo and in vitro assessment of the bleaching effectiveness of a brush-off patch containing 3.0% hydrogen peroxide.

Author information

1
Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, 2177, Dalgubeol-daero, Jung-gu, Daegu, 41940, Republic of Korea.
2
Department of Dental Hygiene, College of Science & Technology, Kyungpook National University, 2559, Gyeongsang-daero, Sangju-si, Gyeongsangbuk-do, Republic of Korea.
3
LG Household & Health Care Co. Research Park, 175, Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
4
Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, 2177, Dalgubeol-daero, Jung-gu, Daegu, 41940, Republic of Korea.
5
Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, 2177, Dalgubeol-daero, Jung-gu, Daegu, 41940, Republic of Korea. kbsong@knu.ac.kr.

Abstract

OBJECTIVES:

To evaluate the efficacy of a brush-off patch containing 3.0% hydrogen peroxide, which is a new over-the-counter (OTC) product for tooth whitening, and determine the optimal protocol for use.

MATERIALS AND METHODS:

We performed an in vitro study using hydroxyapatite specimens and a clinical trial involving 140 volunteers. The brush-off patch was applied to the specimens (in vitro) or the maxillary anterior teeth (in vivo; 14 days) for 10 min twice daily (case 10 group) or 30 min once daily (case 30 group). We also included control groups in both experiments. Lightness (L*), redness (a*), and yellowness (b*) values were measured using a colorimeter. In the in vivo study, color changes were measured at baseline and 7 and 14 days after the start of patch application. The overall color change (ΔE) was statistically analyzed.

RESULTS:

In the in vitro study, the color change (ΔE*) after the experiment was significantly different between the two case groups and the control group (p < 0.001). In the in vivo study, the case groups showed color changes at both 7 and 14 days after patch application. In particular, the change in the case 30 group was significantly more prominent on day 14 than on day 7 (p < 0.05).

CONCLUSION:

Our findings suggest that brush-off patches containing 3.0% hydrogen peroxide are effective OTC products for tooth whitening.

CLINICAL RELEVANCE:

For best results, brush-off patches containing 3.0% hydrogen peroxide can be applied once daily for 30 min.

KEYWORDS:

Bleaching; Brush-off patch; Hydrogen peroxide; Tooth discoloration

PMID:
30327952
DOI:
10.1007/s00784-018-2675-8

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