Format

Send to

Choose Destination
J Pediatr Urol. 2018 Dec;14(6):486-493. doi: 10.1016/j.jpurol.2018.08.004. Epub 2018 Sep 19.

Sexual orientation of 46, XX patients with congenital adrenal hyperplasia: a descriptive review.

Author information

1
Postgraduate Program in Medicine and Human Health, Bahiana School of Medicine and the Department of Urology, Federal University of Bahia, Salvador, Bahia, Brazil.
2
Postgraduate Program in Medicine and Human Health, Bahiana School of Medicine and the Department of Urology, Federal University of Bahia, Salvador, Bahia, Brazil. Electronic address: ubarroso@uol.com.br.

Abstract

BACKGROUND:

Congenital adrenal hyperplasia (CAH) consists of a group of diseases characterized by an enzyme deficiency, particularly 21-hydroxylase deficiency. The condition may present in the simple virilizing form or in the salt-wasting form, with varying degrees of genital ambiguity. The non-heterosexual orientation is used in gender studies fields and includes bisexual, homosexual, Lesbians, gays, bissexuals, transgender, intersex, and others.

OBJECTIVE:

The objective of this study was to evaluate the frequency of non-heterosexual orientation in patients with CAH, in an attempt to identify biological factors possibly associated with this occurrence.

METHODS:

This was a descriptive review of observational studies on the sexual orientation of patients with CAH published between 1985 and 2016, as listed in PubMed.

RESULTS:

Various studies have been performed to establish the relationship between CAH and non-heterosexual orientation. Non-heterosexual orientation is more prevalent in patients with more advanced Prader stages and those with the null and I2-splice genotype.

CONCLUSION:

The prevalence of homosexuality and bisexuality is greater in patients with CAH in relation to the general population.

KEYWORDS:

Congenital adrenal hyperplasia; Prader; Sexual orientation

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center