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Best Pract Res Clin Anaesthesiol. 2018 Jun;32(2):101-111. doi: 10.1016/j.bpa.2018.06.012. Epub 2018 Jul 3.

Procedure-Specific Pain Management (PROSPECT) - An update.

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Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Australia.
Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Australia; Anaesthesiology and Pain Medicine, Medical School, University of Western Australia, Perth, Australia. Electronic address:
University of Texas Southwestern Medical School, Dallas, TX, USA.
Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.


Post-operative pain management protocols may be optimised by examining procedure-specific evidence and outcomes. This recognition led to the formation of the PROcedure-SPECific Pain ManagemenT (PROSPECT) collaboration of anaesthesiologists and surgeons. The aim of PROSPECT is to provide practical and evidence-based recommendations to prevent and treat post-operative pain after specific surgical procedures, thereby overcoming the limitations of generic, non-specific guidelines. Updates in the methodology of PROSPECT in 2017 have placed an increased emphasis on the clinical relevance of studies, including a focus on interventions in the context of multimodal analgesia strategies and consideration of risks and benefits of interventions in specific surgical settings. Evidence-based reviews of analgesic measures, including advice on surgical techniques and adjuvants after diverse surgical procedures, have been completed by the PROSPECT collaboration and are accessible on the website ( and published in the peer-reviewed literature. These reviews continue to identify significant gaps in clinically relevant research on post-operative analgesia and are possibly leading to a closing of some of these gaps.


evidence-based; guidelines; outcome; post-operative analgesia; procedure specific; treatment recommendations

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