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Cancer. 2018 Sep 15;124(18):3733-3741. doi: 10.1002/cncr.31635. Epub 2018 Oct 15.

A feasibility study of breast cancer genetic risk assessment in a federally qualified health center.

Author information

1
Section of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
2
Institute for Health Research and Policy, School of Public Health, University of Illinois at Chicago, Chicago, Illinois.
3
Chicago Family Health Center, Chicago, Illinois.
4
Section of General Internal Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
5
Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

Abstract

BACKGROUND:

The US Preventive Services Task Force (USPSTF) endorses routine screening for genetic risk of breast and/or ovarian cancer as a component of primary health care. Implementation of this recommendation may prove challenging, especially in clinics serving disadvantaged communities.

METHODS:

The authors tested the feasibility of implementing the USPSTF mandate at a federally qualified health center (FQHC) to identify women who were eligible for genetic counseling (GC). A 12-month usual-care phase was followed by a 12-month intervention phase, during which time cancer genetic risk assessment (CGRA) was systematically performed for all women aged 25 to 69 years who presented for an annual examination. Women who were eligible for GC were recruited to participate in the study.

RESULTS:

After initiating CGRA, 112 women who were eligible for GC consented to study participation, and 56% of them received a referral for GC from their primary care physician. A subgroup of 50 participants were seen by the same primary care physician during both the usual-care and intervention phases. None of these patients was referred for GC during usual care, compared with 64% after the initiation of CGRA (P < .001). Only 16% of referred participants attended a GC session.

CONCLUSIONS:

Implementing USPSTF recommendations for CGRA as a standard component of primary health care in FQHCs is feasible and improves referral of minority women for GC, but more work is needed to understand the beliefs and barriers that prevent many underserved women from accessing cancer genetic services.

KEYWORDS:

breast cancer; genetic counseling; genetic susceptibility; health disparities; risk assessment

PMID:
30320429
PMCID:
PMC6214782
[Available on 2019-10-15]
DOI:
10.1002/cncr.31635
[Indexed for MEDLINE]

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