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Med Gas Res. 2018 Sep 25;8(3):116-120. doi: 10.4103/2045-9912.241077. eCollection 2018 Jul-Sep.

Potential application value of xenon in stroke treatment.

Author information

1
Department of Neurosurgery & Brain and Nerve Research Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
2
Department of Neurology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.

Abstract

Stroke is an acute disease with extremely high mortality and disability, including ischemic stroke and hemorrhagic stroke. Currently only limited drugs and treatments have been shown to have neuroprotective effects in stroke. As a medical gas, xenon has been proven to have neuroprotective effect in considerable amount of previous study. Its unique properties are different from other neuroprotective agents, making it is promising to play a special therapeutic role in stroke, either alone or in combination with other treatments. In this article, we aim to review the role of xenon in the treatment of stroke, and summarize the mechanism of using xenon to produce therapeutic effects after stroke according to the existing research. Moreover, we intend to explore and demonstrate the feasibility and safety of xenon for clinical treatment of stroke. Despite the disadvantages of difficulty in obtaining and being expensive, as long as the use of reasonable methods, xenon can play an important role in the treatment of stroke.

KEYWORDS:

brain diseases; ischemia; neuroprotective effects; stroke; xenon

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