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Cancer Discov. 2018 Dec;8(12):OF18. doi: 10.1158/2159-8290.CD-RW2018-176. Epub 2018 Oct 12.

Antibody-Dependent Cellular Cytotoxicity Renders Macrophages Immunosuppressive.

[No authors listed]

Abstract

Therapeutic antibodies result in ADCP that upregulates PD-L1 and IDO on macrophages.

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