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Folia Morphol (Warsz). 2018 Oct 12. doi: 10.5603/FM.a2018.0095. [Epub ahead of print]

Anatomical variations and dimensions of arteries in the anterior part of the circle of Willis.

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Institute of Anatomy, Faculty of Medicine, University of Prishtina, 10000 Prishtina, Kosovo.



The aim of this study was to investigate different anatomic variations and dimensions of anterior part of the CW and their prevalence on Kosovo's population.


This is an observative descriptive and retrospective study performed at the University Clinical Center, Clinic of Radiology. The three-dimensional time-of-flight (TOF) technique was used for MRA imaging to evaluate the anatomy of the CW in 513 adults without clinical manifestations for cerebrovascular disease. The diameters of arteries of the CW were measured and variations were recorded.


The complete anterior part of CW was found in 64.3% of cases, more evident aboutfemale at about 66% than male 62.2%. Morphologic variations of the ACA1 are agenesis or hypoplasia in 5.65%, fusion of the ACAs on a short distance in 6.5% and fusion of the ACA on a long distance in 2.5%, median ACA is presented in 11 examined patients or 2.1%. Normal ACoA was seen in 68.2%, hypoplasia or absence 15.66%, double ACoA in 0.6% and fenestrations in 3.89%. The mean calibrations of the vessels were measured as 2.04 mm in right A1, 2.06 mm in left A1 and 1.16 mm of ACoA. While, 14.1 mm length of right A1, 13.87 mm of left A1 and 2.99 m of ACoA.


Knowledge of the variations and diameter of the anterior part of the CW has a great importance in determination of anatomical variations and diameter in general populations, also, in interventional radiology for various endovascular interventions as well as during anatomy lessons.


CW; anterior part of circle of Willis; dimensions of ACA; dimensions of ACoA; variations of anterior part

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