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Neuroradiology. 2018 Dec;60(12):1253-1266. doi: 10.1007/s00234-018-2103-4. Epub 2018 Oct 11.

CT and MR imaging of orbital inflammation.

Author information

1
Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. T.A.Ferreira@lumc.nl.
2
Department of Radiology, Hospital da Luz, Estrada Nacional 10, km 37, 2900-722, Setubal, Portugal.
3
Department of Ophthalmology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
4
Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
5
Department of Radiology, C.J.Gorter Center for High-field MRI, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

Abstract

PURPOSE:

Orbital inflammation can be idiopathic or in the context of a specific disease and it can involve different anatomical orbital structures. On imaging, inflammatory disease is frequently mistaken for infection and malignant tumors, and its underlying cause is often not determined. Through this article we aim to improve orbital inflammation diagnosis and underlying inflammatory diseases recognition.

METHODS:

The imaging protocols and characteristics of orbital inflammation were reviewed.

RESULTS:

A decision tree for the evaluation of these patients is provided. First, a combination of clinical and radiological clues is used to recognize inflammation, in particular to differentiate it both from orbital infection and tumor. Subsequently, different radiological patterns are recognized, often allowing the differentiation of the several orbital inflammatory diseases.

CONCLUSION:

The use of adequate imaging protocols and subsequent evaluation allow the recognition of an orbital lesion as inflammatory and the diagnosis of the underlying inflammatory disease. All in all, a proper treatment can be established, and at times, a biopsy can be avoided.

KEYWORDS:

CT; Diffusion-weighted imaging; MRI; Orbital inflammation; Orbital inflammatory diseases

PMID:
30310941
PMCID:
PMC6244997
DOI:
10.1007/s00234-018-2103-4
[Indexed for MEDLINE]
Free PMC Article

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