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Cell Host Microbe. 2018 Oct 10;24(4):463-465. doi: 10.1016/j.chom.2018.09.018.

Open Sesame: New Keys to Unlocking the Gate to Norovirus Infection.

Author information

1
Institute of Virology and Cell Biology, University of Luebeck, Luebeck, Germany.
2
Institute of Virology and Cell Biology, University of Luebeck, Luebeck, Germany. Electronic address: stefan.taube@uni-luebeck.de.

Abstract

Three recent papers highlight the impact of an entry receptor on murine norovirus pathogenesis. CD300lf was shown to be the first proteinaceous entry receptor for a norovirus, specialized intestinal epithelial cells constitute the reservoir for persistence, and a new link between the receptor and a lipid biosynthetic enzyme was revealed.

PMID:
30308149
DOI:
10.1016/j.chom.2018.09.018

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