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Physiology (Bethesda). 2018 Nov 1;33(6):384-393. doi: 10.1152/physiol.00027.2018.

Energy Constraint as a Novel Mechanism Linking Exercise and Health.

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1
Evolutionary Anthropology, Duke University , Durham, North Carolina.

Abstract

Humans and other species adapt dynamically to changes in daily physical activity, maintaining total energy expenditure within a narrow range. Chronic exercise thus suppresses other physiological activity, including immunity, reproduction, and stress response. This exercise-induced downregulation improves health at moderate levels of physical activity but can be detrimental at extreme workloads.

PMID:
30303776
DOI:
10.1152/physiol.00027.2018
[Indexed for MEDLINE]
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