Format

Send to

Choose Destination
Clin Transplant. 2018 Dec;32(12):e13421. doi: 10.1111/ctr.13421. Epub 2018 Oct 26.

Assessment of perioperative surgical complications in pediatric kidney transplantation: A comparison of pre-emptive and post-dialysis recipients.

Author information

1
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
2
Division of Urology, The Hospital for Sick Children, Toronto, Ontario, Canada.
3
Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
4
Institute of Urology, St. Luke's Medical Center, NCR, Quezon City, Philippines.
5
Department of Surgery, University of New Mexico, Albuquerque, New Mexico.

Abstract

PURPOSE:

To determine whether there is a benefit to pre-emptive kidney transplantation in reducing surgical complications in pediatric population.

METHODS:

A retrospective review of kidney transplantations in our institution from 2000 to 2015 was performed. Intra- and postoperative complication rates and one-year graft survival were compared in their respective donor type groups (pre-emptive DD vs post-dialysis DD; pre-emptive LD vs post-dialysis LD).

RESULTS:

A total of 318 patients were identified (pre-emptive DD, n = 21; post-dialysis DD, n = 145; pre-emptive LD, n = 54; post-dialysis LD, n = 98). Between the DD groups, post-dialysis DD group was more likely to be female (P = 0.017). There was no difference in rates of intraoperative complications or graft loss (P = 0.365 and 1.000, respectively). Post-dialysis DD groups were more likely to have postoperative complications (9.5% vs 35.1%, P = 0.023), but no difference in complications with Clavien-Dindo grade 3 or higher was found (P = 0.130). Between the LD groups, post-dialysis LD group was more likely to be females (P = 0.017) and with intrinsic renal (non-urological/structural) ESRD etiology (P = 0.003). There was no difference in rates of intra-and postoperative complications or graft loss (P = 0.353, P = 0.605, and P = 0.616, respectively).

CONCLUSIONS:

Overall, there are similar perioperative complication rates between pediatric pre-emptive and post-dialysis kidney transplant recipients.

KEYWORDS:

complications; kidney transplantation; post-dialysis; pre-emptive

PMID:
30303568
DOI:
10.1111/ctr.13421
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center