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Indian J Pathol Microbiol. 2018 Oct-Dec;61(4):580-582. doi: 10.4103/IJPM.IJPM_479_17.

Duodenal gangliocytic paraganglioma: A rare cause for gastrointestinal polyp.

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Department of Histopathology, Sir Ganga Ram Hospital, New Delhi, India.
Institute of Liver Gastroenterology and Pancreatico-Biliary Sciences, Sir Ganga Ram Hospital, Rajender Nagar, New Delhi, India.


Duodenal gangliocytic paragangliomas are rare neoplasms often arising in the duodenum in close proximity to the ampulla of Vater. These neoplasms are considered to have a benign behavior with lymph node metastases being a rare phenomenon and distant metastases even more so. Although a standardized treatment has not been determined, a margin-free tumor resection seems to be the best treatment modality. We report herein the case of a 36-year-old female who presented with abdominal pain and was found to have a polyp in the second part of duodenum which was excised endoscopically. Histopathology and immunohistochemistry revealed characteristic features of this rare tumor.


Differential diagnosis; duodenal polyp; gangliocytic paraganglioma

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