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Audiol Neurootol. 2018;23(3):145-151. doi: 10.1159/000493083. Epub 2018 Oct 9.

Hyperbaric Oxygen Therapy as Concurrent Treatment with Systemic Steroids for Idiopathic Sudden Sensorineural Hearing Loss: A Comparison of Three Different Steroid Treatments.

Author information

1
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japanseijih@hama-med.ac.jp.
2
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
3
Yamahoshi ENT Clinic, Hamamatsu, Japan.
4
Department of Otolaryngology, Shizuoka Saiseikai General Hospital, Shizuoka, Japan.
5
Irie ENT Clinic, Shizuoka, Japan.

Abstract

We analyzed 356 patients with idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy and systemic steroids (n = 161), systemic steroids alone (n = 160), or intratympanic and systemic steroids (n = 35). The main outcome measure was the hearing recovery rate. The effect of other variables, including the initial averaged 5-frequency hearing level, patient age, interval between the onset of symptoms and treatment, presence of vertigo as a complication, presence of diabetes mellitus, smoking history, and presence of hypertension, on the hearing recovery rate was also evaluated. The overall hearing recovery rate was significantly higher for the patients treated with hyperbaric oxygen therapy and systemic steroids than for those treated with systemic steroids alone (p < 0.001) or systemic and intratympanic steroids (p < 0.001). The presence of vertigo negatively affected hearing recovery. Our findings suggest that hyperbaric oxygen therapy confers a significant additional therapeutic benefit when used in combination with steroid therapy for idiopathic sudden sensorineural hearing loss.

KEYWORDS:

Hearing impairment; Hyperbaric oxygen; Intratympanic steroid; Steroid; Sudden hearing loss; Treatment outcome

PMID:
30300887
DOI:
10.1159/000493083
[Indexed for MEDLINE]

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