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J Psychiatr Res. 2018 Nov;106:69-73. doi: 10.1016/j.jpsychires.2018.09.011. Epub 2018 Sep 19.

Views of the importance of psychiatric genetic research by potential volunteers from stakeholder groups.

Author information

1
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA, 94305-5717, USA. Electronic address: LWRoberts.author@gmail.com.
2
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA, 94305-5717, USA.

Abstract

Few studies have explored potential volunteers' attitudes toward genetic research. To address this gap in the literature, we developed an empirical project to document views held by individuals who may wish to enroll in genetic studies involving mental disorders. People living with mental illness, family members of people with mental illness, and community comparison volunteers were queried regarding their views on the importance of genetic research generally, in comparison with medical research, and in relation to 12 health conditions categorized in four types. T-tests and univariate and multivariate analysis of variance were used as appropriate. Participants expressed support for the importance of genetic research (mean = 9.43, scale = 1-10) and endorsed genetic research more highly compared with non-genetic medical research (mean = 9.43 vs. 8.69, P value = <0.001). The most highly endorsed genetic research was for cognitive disorders, followed by mental illness disorders, physical illness disorders, and addiction disorders (means = 8.88, 8.26, 8.16 and 7.55, respectively, P value = <0.001). Overall, this study provides evidence of strong endorsement of genetic research over non-genetic research by potential volunteers.

KEYWORDS:

Community groups; Disorder types; Gender; Genetic research; Non-genetic research; Race/ethnicity

PMID:
30292779
PMCID:
PMC6333463
[Available on 2019-11-01]
DOI:
10.1016/j.jpsychires.2018.09.011

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