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Medicine (Baltimore). 2018 Oct;97(40):e12507. doi: 10.1097/MD.0000000000012507.

Phosphaturic mesenchymal tumor and related wound problem.

Author information

1
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai.
2
Department of Dermatology, The Second Hospital Affiliated to Jiaxing University, Jiaxing, Zhejiang, China.

Abstract

INTRODUCTION:

Phosphaturic mesenchymal tumor mixed connective tissue type (PMT/MCT) is the most common type (up to 90%) of phosphaturic mesenchymal tumor (PMT), a rare clinicopathologic entity. Besides overproduction of fibroblast growth factor 23 (FGF23), there is a big variation of immunohistochemical characteristic across types of PMT, which makes it difficult to obtain an early diagnosis of PMT/MCT. As a benign tumor, PMT/MCT usually happens in subcutaneous tissues and leads to nonhealing of wound. A complete excision of PMT/MCT facilitates wound healing.

CONCLUSIONS:

Review of the existing evidence indicates that early diagnosis of PMT/MCT is critically important when treating PMT/MCT wound. Hence standardization of early diagnosis for PMT/MCT is mandated.

PMID:
30290606
PMCID:
PMC6200523
DOI:
10.1097/MD.0000000000012507
[Indexed for MEDLINE]
Free PMC Article

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