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Cell. 2018 Oct 4;175(2):307-309. doi: 10.1016/j.cell.2018.09.025.

Aster: A New Star in Cholesterol Trafficking.

Author information

1
Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
2
Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA; Departments of Physiology and Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: ajay.chawla@ucsf.edu.

Abstract

Life evolved in an aqueous environment, necessitating the evolution of carrier proteins to shuttle lipophilic molecules within and between cells. Sandhu et. al. (2018) report the discovery of a long-sought-after cholesterol carrier protein, named Aster, which transports cholesterol from the plasma membrane to the endoplasmic reticulum.

PMID:
30290136
DOI:
10.1016/j.cell.2018.09.025
[Indexed for MEDLINE]

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