Polymethylmethacrylate-induced nodules of the lips: Clinical presentation and management by intralesional neodymium:YAG laser therapy

Dermatol Ther. 2019 Jan;32(1):e12755. doi: 10.1111/dth.12755. Epub 2018 Nov 4.

Abstract

The lips are essential part of the beauty and attractiveness of the human face. Lip augmentation has become an increasingly used method to improve appearance. Soft tissue fillers are the most commonly used tools. Permanent fillers, however, have been associated with unwanted side effects after lip augmentation. In the present article the present authors will focus on permanent fillers based on polymethylmethacrylate (PMMA). The present authors provide a short review on PMMA fillers and known associated adverse events. The present authors provide a critical review of treatment options. Illustrated by clinical cases The present authors report our preferred treatment of PMMA nodules on lips by intralesional neodymium:YAG laser and blunt suction cannula with or without minor surgery.

Keywords: intralesional laser therapy; lip augmentation; nodules; permanent fillers; polymethylmethacrylate.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cosmetic Techniques / adverse effects*
  • Dermal Fillers / administration & dosage
  • Dermal Fillers / adverse effects*
  • Esthetics
  • Female
  • Granuloma, Foreign-Body / etiology
  • Granuloma, Foreign-Body / pathology
  • Granuloma, Foreign-Body / surgery*
  • Humans
  • Laser Therapy / adverse effects
  • Laser Therapy / instrumentation*
  • Lasers, Solid-State / adverse effects
  • Lasers, Solid-State / therapeutic use*
  • Lip / pathology
  • Lip / surgery*
  • Middle Aged
  • Polymethyl Methacrylate / administration & dosage
  • Polymethyl Methacrylate / adverse effects*
  • Rejuvenation
  • Risk Factors
  • Suction
  • Treatment Outcome

Substances

  • Dermal Fillers
  • Polymethyl Methacrylate