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Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Nov;35(11):2168-2174. doi: 10.1080/19440049.2018.1520397. Epub 2018 Oct 3.

Effect of Zingiber officinale Roscoe essential oil in fungus control and deoxynivalenol production of Fusarium graminearum Schwabe in vitro.

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a Department of Health Basic Sciences, Laboratory of Toxicology , State University of Maringá , Maringá , Brazil.
b Department of Food Science , State University of Londrina , Londrina , Brazil.
c Department of Food , Federal Technological University of Paraná , Medianeira , Brazil.


Members of the Fusarium genus are capable of contaminating agricultural commodities, compromising the quality of maize and other grains, which leads to severe quality and yield losses. Contamination with mycotoxins is also a concern. Essential oils are possible alternatives to the use of synthetic pesticides for control of fungal contamination, as many have antifungal and anti-mycotoxigenic properties and are innocuous to human health. They also do not cause any sort of microbial resistance and do not promote environmental pollution. The aim of this study was to evaluate the antifungal and anti-mycotoxigenic effects of Zingiber officinale Roscoe essential oil (GEO) upon Fusarium graminearum Schwabe in vitro. The essential oil was extracted by hydrodistillation and analysed by GC/MS. Antifungal and anti-mycotoxigenic activities were assessed by HPLC/UV by quantifying ergosterol and deoxynivalenol (DON), respectively. Results indicated that GEO inhibited ergosterol production at a concentration of 1000 µg/mL and DON production at a concentration of 500 µg/mL, evidencing that the anti-mycotoxigenic effect is independent of the antifungal effect due to its probable direct action upon toxin biosynthesis.


Deoxynivalenol; Fusarium graminearum; anti-mycotoxigenic activity; antifungal; ginger

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