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Child Obes. 2019 Jan;15(1):31-39. doi: 10.1089/chi.2018.0171. Epub 2018 Oct 2.

Maternal Prepregnancy Overweight and Obesity Are Associated with Reduced Physical Fitness But Do Not Affect Physical Activity in Childhood: The Amsterdam Born Children and Their Development Study.

Author information

1
1 Department of Pediatrics, Amsterdam Public Health Research Institute, Amsterdam UMC, Emma Children's Hospital, Vrije Universiteit, Amsterdam, the Netherlands.
2
2 Department of Obstetrics and Gynecology, Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
3
3 EMGO Institute for Health and Care Research, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.
4
4 Institute of Sport Science, University of Graz, Graz, Austria.
5
5 Department of Public Health, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
6
6 Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, University of Amsterdam, the Netherlands.
7
7 Department of Pediatric Cardiology, Amsterdam UMC, Emma Children's Hospital, University of Amsterdam, Amsterdam, the Netherlands.

Abstract

BACKGROUND:

Maternal overweight/obesity during pregnancy increases offspring's risks of obesity and cardiovascular disease (CVD). A possible pathway is by reduced physical fitness and physical activity (PA) levels in children of overweight/obese mother. We assessed whether maternal prepregnancy overweight/obesity independently determines cardiorespiratory fitness (CRF), muscular strength, moderate-to-vigorous physical activity (MVPA), and sedentary behavior (SB) in 8- to 9-year-old children. We also assessed whether child's fat mass (FM) mediates these associations.

METHODS:

One hundred ninety-four children of Dutch ethnicity aged 8.6 (± 0.4) years were randomly selected from a prospective birth cohort, the Amsterdam Born Children and their Development (ABCD) study. CRF was assessed by the 20-m multistage shuttle run test (20-m MSRT), muscular strength by hand dynamometry, and MVPA and SB by accelerometry. The association of prepregnancy body mass index (BMI) ≥ 25 kg/m2 with these outcome measures was assessed by multivariable linear regressions.

RESULTS:

Mean (± standard deviation) attained 20-m MSRT stage was 5.3 (± 1.7). Compared with children from normal weight women, children of women with prepregnancy overweight/obesity attained a 0.80 (95% confidence interval: 0.15-1.50) lower stage, adjusted for child's sex and MVPA. This association was not mediated by birthweight or child's FM at age 5 years. Maternal prepregnancy overweight/obesity was not associated with child's muscular strength, MVPA, or SB.

CONCLUSIONS:

Maternal prepregnancy overweight/obesity was associated with reduced childhood CRF, but not with muscular strength, PA, or SB. Birthweight and FM at age 5 years did not mediate this association. Reduced CRF may partly explain the increased CVD risk in children of overweight/obese women.

KEYWORDS:

cardiorespiratory fitness; developmental programming; maternal obesity; maternal overweight; obesity; offspring health

PMID:
30280927
DOI:
10.1089/chi.2018.0171

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