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J Pediatr Neurosci. 2018 Jul-Sep;13(3):331-333. doi: 10.4103/JPN.JPN_53_18.

Neurocutaneous Melanosis with Bilateral Temporal Lobe Lesions without Leptomeningeal Enhancement: A Distinct Entity or Subtype.

Author information

1
Department of Neurosurgery, Command Hospital (Southern Command), Pune, Maharashtra, India.
2
Department of Neurosurgery, Command Hospital (Central Command), Lucknow Cantonment, Lucknow, Uttar Pradesh, India.
3
Department of Radiology, Command Hospital (Central Command), Lucknow Cantonment, Lucknow, Uttar Pradesh, India.

Abstract

Neurocutaneous melanosis (NCM) is a rare congenital disorder. Most of the cases described in literature for this entity have involvement of the leptomeninges and other structures of brain such as brain stem, temporal lobes, and spinal meninges and no involvement of leptomeninges and presence of lesions in bilateral temporal lobes. NCM without the involvement of leptomeninges should be considered a distinct entity as the prognosis is favorable as compared to cases with leptomeningeal involvement who develop early hydrocephalus and multiple cranial nerve palsies.

KEYWORDS:

Bilateral; intracranial melanoma; neurocutaneous melanosis

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