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J Neurosci Rural Pract. 2018 Oct-Dec;9(4):644-646. doi: 10.4103/jnrp.jnrp_16_18.

Neurobrucellosis Presenting as Acute Psychosis.

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Department of Neurology, Government Medical College, Superspeciality Hospital, Srinagar, Jammu and Kashmir, India.
Department of Psychiatry, Government Medical College, Srinagar, Jammu and Kashmir, India.
Department of Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.


A 45-year-old female without any past or family history of psychiatric illness presented to the emergency department with complaints of abnormal behavior, irrelevant talking, restlessness, episodic crying, and decreased sleep of 2-day duration. On detailed interview, the attendants gave a history of an intermittent headache of 6-month duration and hearing impairment of 4-month duration. On investigation, her cerebrospinal fluid was reactive, and brucella titers were positive. She received appropriate treatment for 6 months and a short course of antipsychotics. Her symptoms settled, but she had persistent hearing loss. Psychosis as well as hearing loss is a very rare presentation of brucellosis. The case highlights the importance of considering neurobrucellosis as a differential diagnosis in patients with any unexplained neuropsychiatric symptoms such as acute psychosis or hearing loss.


Brucella meningitis; brucella psychosis; neurobrucellosis; sensorineural hearing loss.

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