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Sci Rep. 2018 Sep 28;8(1):14562. doi: 10.1038/s41598-018-32574-0.

Molecular diversity and antimicrobial susceptibility of Listeria monocytogenes isolates from invasive infections in Poland (1997-2013).

Author information

1
National Medicines Institute, Department of Epidemiology and Clinical Microbiology, Warsaw, 00-725, Poland.
2
Nicolaus Copernicus University, Department of Genetics, Toruń, 87-100, Poland. goc@umk.pl.
3
National Tuberculosis and Lung Diseases Research Institute, Department of Microbiology, Warsaw, 01-138, Poland.
4
University of Turin, Department of Veterinary Sciences, Grugliasco, 10095, Italy.
5
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Brescia, 25124, Italy.
6
US Food and Drug Administration, College Park, Maryland, 20740, USA.

Abstract

The epidemiology of invasive listeriosis in humans appears to be weakly characterized in Poland, the sixth most populous member state of the European Union. We obtained antimicrobial susceptibility data, PCR-serogroups and genotypic profiles for 344 invasive isolates of Listeria monocytogenes, collected between 1997 and 2013 in Poland. All isolates were susceptible to the 10 tested antimicrobials, except one that was resistant to tetracycline and minocycline and harbored the tet(M), tet(A) and tet(C) genes. Overall, no increasing MIC values were observed during the study period. Four PCR-serogroups were observed: IVb (55.8%), IIa (34.3%), IIb (8.1%) and IIc (1.8%). We identified clonal complexes (CCs) and epidemic clones (ECs) previously involved in outbreaks worldwide, with the most prevalent CCs/ECs being: CC6/ECII (32.6%), CC1/ECI (17.2%), CC8/ECV (6.1%) and CC2/ECIV (5.5%). The present study is the first extensive analysis of Polish L. monocytogenes isolates from invasive infections.

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