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Chem Commun (Camb). 2018 Oct 11;54(82):11586-11589. doi: 10.1039/c8cc05753b.

Paclitaxel-induced formation of 3D nanocrystal superlattices within injectable protein-based hybrid nanoparticles.

Author information

1
Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro Yuseong-gu, Daejeon 34141, Republic of Korea. yoonsung@kaist.ac.kr.

Abstract

Self-assembly of monodisperse superparamagnetic iron oxide nanocrystals into a close-packed, three-dimensional (3D) superlattice is designed within cross-linked protein-based nanoparticles composed of human serum albumin and polyethylene glycol. The prepared nanoparticles are very stable in serum and exhibit a high T2 relaxivity as well as anti-cancer activity, indicating the practical benefits of ordering nanocrystals.

PMID:
30264087
DOI:
10.1039/c8cc05753b
[Indexed for MEDLINE]

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