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Chem Commun (Camb). 2018 Oct 11;54(82):11618-11621. doi: 10.1039/c8cc06792a.

Co-assembling FRET nanomedicine with self-indicating drug release.

Author information

1
Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China. goumaling@scu.edu.cn.

Abstract

Two lipophilic fluorescent prodrugs co-assembled into nanoaggregates with the ability to release FRET-indicated drugs, which was used to investigate the role of reduction-responsive linkers on drug release kinetics in the cytoplasm and physiologically relevant media in a visualized, noninvasive manner.

PMID:
30264076
DOI:
10.1039/c8cc06792a

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